Our body is composed of trillions of differentiated cells maintaining structural, physiological and functional homeostasis in various organs. Cell therapy has been highlighted as a promising approach to treat disorders that were not efficiently curable with conventional drug-based therapeutics. Especially, not only the cells themselves, but the cell-derived materials also have shown great potential in treating various diseases and regeneration of damaged tissue. We develop novel cell-based therapeutics and engineering cell-derived materials for therapeutic applications. We are also interested in designing novel devices that can mediate efficient cell transplantation and subsequent therapeutic efficacy.